DOSING

VYXEOS provides a finite
treatment duration1

Treatment with VYXEOS gives your patients additional
flexibility between induction and consolidation cycles. VYXEOS is
administered through up to 2 cycles of induction and consolidation

First induction1

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90-minute infusion

On Days 1, 3, and 5

Daunorubicin 44 mg/m2
and cytarabine 100 mg/m2

Second induction (if needed)

For patients who do not achieve remission after first induction, a second induction may be started
2 to 5 weeks later at the same dose (daunorubicin 44 mg/m2 and cytarabine 100 mg/m2)
on Days 1 and 3.1

CONSOLIDATION1

Patients could receive consolidation or proceed
to HSCT.

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90-minute infusion

On Days 1 and 3

Daunorubicin 29 mg/m2
and cytarabine 65 mg/m2

Second consolidation (if needed)

For patients who do not show disease progression or unacceptable toxicity, a second consolidation may be started 5 to 8 weeks after the start of the first consolidation at the same dose (daunorubicin 29 mg/m2 and cytarabine 65 mg/m2)
on Days 1 and 3.1

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